孙海涛
孙海涛

检验医学部副主任

临床生物样本资源中心主任

副主任医师,副研究员,学术型硕导


联系方式:020-62783242

E-mail:msunhaitao1988@126.com


曾入选“香江学者计划”、“广州市珠江科技新星”、“广东省100位博士博士后创新人物”等人才项目。


研究方向:

● 脑重大疾病(脑肿瘤、脑血管病)精准检验诊断

● 临床生物样本资源库建设及肿瘤精准诊断

● 组织透明技术在脑重大疾病机制研究中的应用

● 脑-肠-轴在脑出血疾病机制中的作用及干预策略


招生专业:

●  临床检验诊断学、神经外科


招生层次:

●  学术型硕士

●  专业型硕士


主持课题:

1.  近年来先后承担国家自然科学基金青年项目1项、广东省自然科学基金2项、香港医疗卫生研究基金HMRF 1项、南方医科大学青年科技人员培育项目1项目、南方医科大学珠江医院青年人才培育项目(杰青培育)1项。


代表作论文/著作: 

  1. Jiajia Zhao*, Hei Ming Lai, Yuwei Qi, Dian He, Haitao Sun*. Current status of tissue clearing and the path forward in neuroscience [J]. ACS Chemical Neuroscience.  2021, 12 (1), 5-29. (IF: 4.486)

  2. Xiao L, Zheng H, Li J, Wang Q*, Sun H*. Neuroinflammation mediated by NLRP3 inflammasome after intracerebral hemorrhage and potential therapeutic targets [J]. Molecular Neurobiology. 2020, 57: 5130–5149. (IF: 4.50)

  3. Anson Cho Kiu Ng#, Min Yao#, Yin Stephen Cheng, Jing Li, Jiandong Huang, Wutian Wu*, Gilberto Ka Kit Leung*, Haitao Sun*. Protracted morphological changes in the corticospinal tract within the cervical spinal cord after intracerebral hemorrhage in the right striatum of mice [J]. Frontiers in Neuroscience. 2020, 14:506.  (IF: 3.707)

  4. Xu zhao, Jing Li, Haitao Sun*. CD200-CD200R Interaction: An important regulator after stroke [J]. Frontiers in Neuroscience. 2019,13:840. (IF: 3.648)

  5. Min Yao#, Haitao Sun#, Qiuju Yuan, Ning Li, Heng Li, Yinjuan Tang, Gilberto KK Leung*, Wutian Wu*. Targeting proteoglycan receptor PTPσ restores sensory function after spinal cord dorsal root injury by activation of Erks/ CREB signaling pathway [J]. Neuropharmacology, 2019,144:208-218 (中科院JCR 1区, IF: 4.367)

  6. Raozhou Lin#, Zhigang Duan#, Haitao Sun#, Man-Lung Fung#, Hansen Chen, Jing Wang, Chi-Fai Lau, Di Yang, Yu Liu, Yanxiang Ni, Zai Wang, Ju Cui, Wutian Wu, Wing-Ho Yung, Ying-Shing Chan, Amy C. Y. Lo , Jun Xia , Jiangang Shen, Jian-Dong Huang*. Kinesin-1 regulates extrasynaptic targeting of NMDARs and neuronal vulnerability towards excitotoxicity [J]. iScience, 2019,13:82–97.

  7. Tian Zhou#, Yiming Zheng#*, Li Sun, Smaranda Ruxandra Badea, Yuanhu Jin, Yang Liu, Alyssa J. Rolfe, Haitao Sun, Xi Wang, Zhijian Chen, Zhaoshuai Huang, Na Zhao, Xin Sun, Jinhua Li, Jianqing Fan, Choogon Lee, Timothy L. Megraw, Wutian Wu, Guixue Wang*, Yi Ren*. Microvascular endothelial cells engulf myelin debris and promote macrophage recruitment and fibrosis after neural injury [J]. Nature Neuroscience, 2019, 22:421–435. (IF: 21.126)

  8. Sun H#, Hou Z#, Yang H, Meng M, Li P, Zou Q, Yang L, Chen Y, Chai H, Zhong H, Yang Z, Zhao J, Lai L, Jiang X*, Xiao Z*. Multiple Systemic Transplantations of Human Amniotic Mesenchymal Stem Cells Exert Therapeutic Effects in an ALS Mouse Model [J].Cell Tissue Res. 2014, 357(3):571-582. (IF: 3.565)

  9. Yang H#, Wang G#, Sun H#, Shu R#, Liu T, Wang C, Liu Z, Zhao Y, Zhao B, Ouyang Z, Yang D, Huang J, Zhou Y, Li S, Jiang X*, Xiao Z*, Li X*, Lai L*.Species-dependent neuropathology in transgenic SOD1 pigs [J].Cell Res. 2014, 24(4):464–481. (中科院JCR 1区, IF: 12.413)

  10. Haitao Sun, Min Yao, Gilberto KK Leung, Wutian Wu*. Manipulation of the proteoglycan receptor PTPσ promotes functional sensory axon regeneration after spinal cord dorsal root crush injury. 8th Academic Congress of International Chinese Neurological Sciences(第八届世界华人外科学术大会), 2018 (May10-13 at Nanchang, China) (oral presentation)

  11. Haitao Sun, Min Yao, Hei Ming Lai, Yin Stephen Chen, Smaranda Ruxandra Badea, Ya Gao, Jiandong Huang, Gilberto Ka Kit Leung, Wutian Wu*.Targeting PTPσ induces functional recovery by enhancing perilesional axon regeneration and attenuating ipsilesional CST degeneration in experimental ICH mice. 2018 World Life Science Conference (2018 世界生命科学大会) (October 27-29, 2018, China National Convention Center, Beijing) (Travel Award)

  12. H. SUN, M. YAO, H. LAI, S.R. Badea , Y. GAO, J. HUANG, G. K. LEUNG, W. WU*.Targeting PTPσ enhances axonal regeneration, remyelination and functional recovery after intracerebral hemorrhage in mice. SfN's 48th annual meeting, Neuroscience 2018(美国神经科学年会) (November 3-7 at the San Diego, CA) (poster presentation)

  13. Xiao KT, Liang XM, Gao Y, Chen MB, Wu DB, Jiang XD, Guo YW, Sun HT*. Effect of human amniotic mesenchymal stem cell transplantation on motor behaviors in hSOD1-G93A mouse models of amyotrophic lateral sclerosis [J]. Chin J Neuromed, 2017, 16(7):649-656. (Chinese)

  14. Song J, Gao Y, Zhuo WB, Yang CY, Xu Y, Ping BH*, Sun HT*. Immunomodulatory effects of human amniotic versus bone marrow-derived mesenchymal stem cells on peripheral blood T lymphocytes in vitro [J]. Nan Fang Yi Ke Da Xue Xue Bao, 2017, 37(6):780-785. (Chinese)  

  15. Hong JQ, Gao Y, Song J, Zhuo WB, Sun HT*, Ping BH*. Comparison of Biological Characteristics and Immunosuppressive Activity between Human Amniotic Mesenchymal Stem Cells and Human Bone Marrow Mesenchymal Stem Cells [J]. Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2016, 24(3):858-864. (Chinese)

  16. Deng YH, Wang XL, Su BJ, Ge ZZ, Guo YW, Sun HT*. Advances in chimeric antigen receptor T-cell immunotherapy (CAR-T) in glioma [J]. J ADV HEALTH 2019, 1(2): 139-144. 


学术任职:

● 中国研究型医院学会临床数据与样本资源库分会委员

● 中国医药生物技术协会组织生物样本库分会质量管理学组委员&数据规范和应用学组委员

● 中国神经科学学会神经损伤与修复分会委员

● 广东省精准医学应用学会分子病理分会常委&神经肿瘤分会常委

●广东省医学会检验医学分会实验室管理学组委员兼秘书&青年检验医师学组成员

● 广东省医学会检验医学分会青年委员会秘书

●广东省医学会精准医学与分子诊断学分会委员

●广东省青年科学家协会会员